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14 Aug 2025
The Diaspora Paradox
On Being The Right Size
In Trump-Modi standoff, ‘egos’ and missteps fuel resentment - The Washington Post
13 Aug 2025
Attention is your scarcest resource
Fast Biology
How China Became the World’s Biggest Shipbuilder
12 Aug 2025
How I Write Posts
Protocols, Not Platforms: A Technological Approach to Free Speech
10 Aug 2025
GPT-5: It Just Does Stuff
The (Un)Making of Environmental Carcinogens
Glucose-Responsive Microneedle Patches For Diabetes Treatment
The Case for Bridge Editors
The Origin of Life on Earth
09 Aug 2025
How to Live Forever and Get Rich Doing It | The New Yorker
08 Aug 2025
GPT-5: Key characteristics, pricing and model card
07 Aug 2025
India’s difficult business environment is improving
India’s financial system has improved dramatically in the past decade
For its next phase of growth, India needs a new reform agenda
05 Aug 2025
Micropayments. Elon Musk thinks he’s got a “major win-win” for news publishers with…micropayments.
31 Jul 2025
I know genomes. Don't delete your DNA
29 Jul 2025
One Question that Will Help You Become Consistent
28 Jul 2025
Dispatches from India
25 Jul 2025
44% of sitting MPs face criminal charges, 5% are billionaires: ADR
24 Jul 2025
Reconstitution Of Circadian Oscillation Of Cyanobacterial KaiC Phosphorylation In Vitro
How A Cell Anticipates the Seasons
Magic Cards and Knowledge Bottles
23 Jul 2025
Bacteria Can Anticipate The Seasons: Photoperiodism In Cyanobacteria
22 Jul 2025
Two billion people don’t have safe drinking water: what does this really mean for them?
Atom vs. RSS
Reading in Slow Motion
The ultra-selfish gene
Notes on Epistemic Collapse
21 Jul 2025
We Can, Must, and Will Simulate Nematode Brains
17 Jul 2025
Putting the “social” into “social contracts”
Just How Many More Successful UBI Trials Do We Need? | by Katie Jgln …
Laura Deming: ‘I wanted to work on the world’s most important problem…
Senolytic Update
The Gene: An Intimate History
Book Review: The Secret Of Our Success
16 Jul 2025
Reflections on OpenAI
[REPOST] Epistemic Learned Helplessness
10 Jul 2025
The Paradox of India - Samir Varma
08 Jul 2025
A tale of two repressors – a historical perspective
07 Jul 2025
Welding and the Automation Frontier
06 Jul 2025
Why Genes In Pieces?
04 Jul 2025
The End of the Millennial Lifestyle Subsidy
The Agentic Web and Original Sin
30 Reflections
02 Jul 2025
What I Learned in 2024
The Mahabharata V1
01 Jul 2025
Reflections on Haskell and Rust
25 Jun 2025
The Scientific Basis For The Somatic Mutation Theory Of Cancer Is Invalid
Viral oncology’s complicated path—from cancer as contagion to today’s immunotherapy
23 Jun 2025
The Political Life Of Mutagens: A History Of The Ames Test
22 Jun 2025
Book Notes: Stoner (1965)
20 Jun 2025
Understanding as an art
Exclusive | DNA Analysis Startup Nucleus Genomics Aims to Rank Embryo…
Can ‘progress studies’ contribute to knowledge? History suggests caution
19 Jun 2025
The most-feared assays
Bruce Ames, 95, Dies; Biochemist Discovered Test for Toxic Chemicals …
A Perspective On The Development Of The Ames Salmonella/Mammalian-Microsome Mutagenicity Assay
Expert Generalists: first three characteristics
How Field Notes went from side project to cult notebook
18 Jun 2025
The Ames Test and the Real World
17 Jun 2025
The Ames Salmonella / Microsome Mutagenicity Assay
16 Jun 2025
Edward B Lewis
Ch 9 - Epidemiology | Core Psychiatry
Drones will realize the promise of suicide terrorism
15 Jun 2025
Strategy Letter V
14 Jun 2025
The Trojan Truck: How Ukraine Just Made Nowhere Safe
Houthi attacks on shipping in Red Sea threaten global consequences - …
13 Jun 2025
Notes on Managing ADHD
12 Jun 2025
Guess I’m A Rationalist Now
10 Jun 2025
LIFE IN THE LAB
Thoughts on thinking
🔭 The Einstein AI model
Harvard’s International Students Are People — Not Pawns
We’ve Got Issues
09 Jun 2025
Rampant AI Cheating Is Ruining Education Alarmingly Fast
Knowledge Work Is Dying — Here’s What Comes Next
08 Jun 2025
The bad science behind expensive nuclear
Why robots are not the answer to US manufacturing reshoring hopes
The Last Question
04 Jun 2025
Do Cellphones Cause Brain Cancer? - The New York Times
American Disruption
03 Jun 2025
Capturing and Colliding
02 Jun 2025
Opinion | Covid’s Deadliest Effect Took Five Years to Appear - The New York Times
Tegmark's Mathematical Universe Defeats Most Proofs Of God's Existence
The Fine-Tuning Argument Simply Works
My Doubts about the Fine-Tuning Argument
How Do You Capture Your Hunches? - by Steven Johnson
28 May 2025
Google’s AI Vision: Make Tech Human Again
27 May 2025
Most AI value will come from broad automation, not from R&D
The Definition of Gene Therapy Has Changed
24 May 2025
I should have loved biology too
Cells are very fast and crowded places
I should have loved biology
Opinion | Come With Me if You Want to Survive an Age of Extinction - The New York Times
Opinion | Jeff Bezos: The hard truth: Americans don’t trust the news …
Facebook Offers Life Raft, but Publishers Are Wary - The New York Tim…
Robot Dexterity Still Seems Hard
21 May 2025
Sometimes the reason you can’t find people you resonate with is because you misread the ones you meet
A history of the Internet, part 1: An ARPA dream takes form
20 May 2025
How To Mark A Book
13 May 2025
A Chance to Build
12 May 2025
Idea machines
11 May 2025
Who Wins Nobel Prizes?
The Human Brain Is a Time Traveler
09 May 2025
How Much Information is in DNA?
08 May 2025
Healing My Family’s Future
Microsoft Earnings, Microsoft’s Core Capability, Amazon Earnings
06 May 2025
Possibly a serious possibility
How to Read a Book a Week
Power to the people: How LLMs flip the script on technology diffusion
Why Techdirt Is Now A Democracy Blog (Whether We Like It Or Not)
04 May 2025
Book Review: Abundance by Ezra Klein and Derek Thompson
01 May 2025
Bluesky’s Quest to Build Nontoxic Social Media | The New Yorker
How to Unleash the Potential of New Energy Technology
Is Steve Ballmer the Most Underrated CEO of the 21st Century?
Three Simple Principles of Trade Policy
30 Apr 2025
Why can’t stinking rich Ivies cope with losing a few hundred million?
29 Apr 2025
Publishers and the Smiling Curve
A Tale of Two Repressors
The Long Way to a Small, Angry Planet
Life is Short
The Elite College Students Who Can’t Read Books
28 Apr 2025
Realtime Editing of Ordered Sequences
24 Apr 2025
A Tale of Two Repressors
21 Apr 2025
The three kinds of non-fiction books
The Ultimate Burnout Guide: Symptoms, Causes, and Prevention
Behind the Scenes of My Interview Research Process — Andy Matuschak Crashes My Crib!
20 Apr 2025
Tech things: OpenAI buys Windsurf, Google retains its lead, and where the hell is Apple?
17 Apr 2025
Trade, Tariffs, and Tech
America Underestimates the Difficulty of Bringing Manufacturing Back
16 Apr 2025
On the Phenomenon of Bullshit Jobs: A Work Rant
15 Apr 2025
The Nonwriter's Guide to Writing A Lot
12 Apr 2025
The Disapproval of the Crowd by Alex Karp
11 Apr 2025
Condensing The Iceberg
10 Apr 2025
The secret architecture of great essays
04 Apr 2025
Progress, stagnation, and flying cars
03 Apr 2025
Ways Of Flourishing
Breakfast for Eight Billion
Against the Trap of Efficiency: The Counterintuitive Antidote to the Time-Anxiety That Haunts and Hampers Our Search for Meaning
02 Apr 2025
Trump's war on science
01 Apr 2025
Things Are Bad At Tesla. They’re About To Get Much Worse.
28 Mar 2025
Mitochondria Are Alive
24 Mar 2025
America Is Watching the Rise of a Dual State
16 Mar 2025
This Habit Will Outlast Every Notes App
14 Mar 2025
AI Antibodies? Really?
11 Mar 2025
China’s Hidden Tech Revolution
07 Mar 2025
How To Decide
Playing God
The Backlash
Elon Musk and spiky intelligence
05 Mar 2025
Biological Age
Birth Of A Science
04 Mar 2025
The Calment Boundary
Immortality, A User's Guide
26 Feb 2025
Life Is More Than an Engineering Problem
24 Feb 2025
Why Do Young Men Migrate?
23 Feb 2025
We Live Like Royalty and Don’t Know It
22 Feb 2025
Designing a Workflow For Thinking
18 Feb 2025
The Technological Singularity
15 Feb 2025
The Long Road to End Tuberculosis
14 Feb 2025
Two biotechs say they’re using AI to conjure drugs from scratch. Their documents suggest otherwise
11 Feb 2025
Thread-safe memory copy
10 Feb 2025
Issue 105: Why is everybody reading Middlemarch right now?
How To Read A Novel
Here’s why we’re not prepared for the next wave of biotech innovation
08 Feb 2025
Observations From India
07 Feb 2025
Do Not Trust Journalists (A Mormon Example)
06 Feb 2025
Why Skyscrapers Became Glass Boxes
The Free Lunch Is Over A Fundamental Turn Toward Concurrency in Software
05 Feb 2025
Opinion | Why Are Housing Costs So High? The Elevator Can Explain Why. - The New York Times
29 Jan 2025
Artificial Wombs When?
27 Jan 2025
The False Promise of Device-Based Education
26 Jan 2025
Echo of Worlds
23 Jan 2025
Science Proceeds One Question at a Time
22 Jan 2025
Rise and Grind: Outperform, Outwork, and Outhustle Your Way to a More Successful and Rewarding Life (Daymond John)
Degrowth can work — here’s how science can help
Ideas matter: How I stopped being a Culture Incel
20 Jan 2025
The EdTech Revolution Has Failed
17 Jan 2025
The Bitter Lesson
16 Jan 2025
REVIEW: Reentry, by Eric Berger
11 Jan 2025
Learning By Writing
Advice That Actually Worked For Me